Dr Shiwani Sharma

Academic Status

College of Medicine and Public Health

place SA Health & Medical Research Institute (Level 6S)
GPO Box 2100, Adelaide 5001, South Australia

Dr Shiwani Sharma pursues cardiovascular research at the Vascular Research Centre, Lifelong Health Theme, South Australian Health and Medical Research Institute (SAHMRI). She is contributing to stem cell research focused on novel adult stem cells involved in vascular regeneration in health and disease. She utilises animal models, cell culture systems and cutting-edge technlogies such as single-cell RNA sequencing, multi-coloured immunolabelling and confocal microscopy for this research. She plans to expand this research to include adult human stem cells for harnessing their therapeutic potential for regenerative medicine.  

Prior to cardiovascular research, Dr Sharma pursued ophthalmic research in the College of Medicine and Public Health for over twenty years. She focused on decipehring the molecular mechanisms underlying genetically predisposed eye diseases, including corneal dystrophies, cataract and glaucoma. She published this research in leading scientific journals, including Nature Genetics, Nature Communications, American Journal of Human Genetics, Human Molecular Genetics and Journal of Cell Science. She presented this research at international and national scientific meetings organised by the International Society for Eye Research, Asia and Oceania Society for Photobiology, and Australian Society of Biochemists and Molecular Biologists as an invited speaker.

Qualifications
  • PhD; Punjab Agricultural University, India
  • MSc; Punjab Agricultural University, India
  • BSc; Guru Nanak Dev University, India
Honours, awards and grants
  • Senior Research Fellowship, CSIR (India); 1989-1991
  • Junior Research Fellowship, CSIR (India); 1987-1989
  • University Merit Scholarship during Master's Program; 1986-1987
Key responsibilities
  • Undertaking and contributing to research
  • Research student training and supervision
  • Research Governance
  • Contributing to generation of research funding
  • Southern Adelaide Clinical Human Research Ethics Committee Member
Teaching interests

Physiology of the human eye and pathophysiology of human eye diseases.

Application of molecular and cell bioloigy methodologies in biomedical research.

Topic lecturer
MMED1005 How Your Body Works
MMED8937 Pathophysiology for Medical Science
MMED3937 Pathophysiology for Medical Science
Supervisory interests
Adult stem cell niche
Microvascular aspects of inflammation and injury
Neovascularisation
Higher degree by research supervision
Completion
Principal supervisor: Genetics and molecular biology of Fuchs' corneal dystrophy (1), Molecular biology of congenital cataract (1), Corneal dystrophy (1), Congenital cataract (2)
Associate supervisor: Biophysical studies in Pseudoexfoliation syndrome (1), Genetics of congenital cataracts (1), Glaucoma genetics (1), Diabetic retinopathy (1)
Higher degree by research student achievements
Alpana Dave

Vice-Chancellor’s Prize for Doctoral Thesis Excellence - APR 2016

Further information

Interested in

  • Improving management of vascular complications for tissue healing and repair
  • Increasing public awareness about common eye diseases

Honours and Masters Research Projects (pptm)